Curebiology Β· AI Therapeutic Intelligence

Evidence-graded biotech diligence

Built live from primary records at PubMed, ClinicalTrials.gov, openFDA, Open Targets, ChEMBL and PubChem. Zero black-box predictions: we surface cited evidence, failure modes, and historical analogs.

Active Indication Scope:πŸŽ—οΈCancer
Token-Linked Β· AI-Enabled

7 Primary Biomedical Registries. Live Traceability.

Every citation is tied directly to primary records at NLM, ClinicalTrials.gov, FDA, EMBL-EBI, and Open Targets. Defensible diligence for biopharma BD, licensing, and venture teams.

PubMedCT.govopenFDAChEMBLPubChemPatents
38M+
Live Indexed Articles & Trials
AUDITABLE
7
Registries Live

NCBI PubMed, ClinicalTrials.gov, openFDA, Open Targets, ChEMBL, PubChem & the USPTO Open Data Portal.

100%
Traceable Registry Data

Zero proprietary black-box data. Every analog and trial outcome links to its primary record.

12+
Failure Modes

On-target toxicity, off-target liabilities, PK/PD hurdles, resistance mutations & safety signals.

Primary-Source Diligence

Traceable failure modes over historical programs

Biotech assets fail for recurring, documented reasons. We cross-reference your candidate against hundreds of terminated and approved analogs to map liabilities early.

MODALITY-SPECIFIC ATTRITIONExplore Workbench β†’
Transparent Literature Mapping

Mechanistic contradictions surfaced directly

We synthesize peer-reviewed literature alongside open clinical endpoints to detect unstated gaps, disputed mechanisms, and translational discrepancies.

PubMed Live QueryCT.gov REST APIopenFDA FAERSOpen Targets PlatformChEMBL & PubChem
CONSULT SCIENCES LTDΒ·CUREBIOLOGYΒ·THERAPEUTIC INTELLIGENCE
The Defensible Moat Β· Not Prediction

Four architectural pillars powering diligence

Biotech due diligence doesn't need speculative predictions. Our moat is built on verifiable biological topologies, structured trial outcomes, contradictory evidence extraction, and workflow UX.

THERAPEUTIC GRAPH

Proprietary Therapeutic Graph

Topological graph linking molecular targets, disease pathways, clinical trials, and bioactive entities.

TRIAL INTELLIGENCE

Structured Trial Intelligence

Granular trial registry indexing: endpoints, stratification, and documented historical termination reasons.

CONTRADICTION ENGINE

Mechanistic Contradiction Engine

Automated semantic detection of conflicting biological assertions and disputed trial claims.

Instant Live Diligence

Run a multi-source pass in seconds

Enter a compound or target below to generate a synthesized diligence dossier from PubMed, ClinicalTrials.gov, and openFDA FAERS. (Requires 15 πŸͺ™ Tokens)

Quick presets:
Live endpoints: PubMed Β· CT.gov Β· openFDA Β· Open Targets
Historical Attrition Taxonomies

Biotech assets don't fail in novel ways. They repeat history.

Most diligence memos rely on pitch decks and self-selected peer comparisons without verifiable rationale. Curebiology extracts historical clinical trials, discontinued analogs, and post-marketing safety signals so your team recognizes the real biological failure modes before deploying resources.

Target Validation
Genetic association scores, CRISPR essentiality, and target safety liabilities.
Attrition Signatures
Prior-phase clinical stops, toxicity profiles, and dose-limiting endpoints.
Literature Verification
Contradictory findings and unverified mechanistic claims graded transparently.
Dynamic modality-specific risk taxonomiesExplore in Workbench β†’
Active Disease Catalog:

Indication workspace (Cancer)

My Overview

Personalized insights for your research journey.

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Papers indexed
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Recruiting trials
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News stories
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Your diligence reports

Research

Explore the shape of the indexed literature.

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Articles by Subtype

Distribution of articles by disease subtype.

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Our Operating Philosophy

A Vision for Auditable Therapeutic Science

Biopharma decisions should never hinge on unverifiable hype, opaque black-box assertions, or uncorroborated pitch decks. We believe every diligence memorandum, asset appraisal, and clinical strategy must carry an immutable, transparent citation chain directly back to primary scientific records.

Saving Dozens of Hours on Every Memo

By synthesizing historical clinical trial failures and attrition causes instantly, biopharma venture and BD teams bypass weeks of tedious manual literature scouring.

CORE PILLAR Β· COMPREHENSIVE CITATIONS

Zero Black-Box Assertions

Every claim, target interaction, and pharmacovigilance alert links directly to open FDA, PubMed, and ChEMBL records so scientific scrutiny remains entirely independent and defensible.

CORE PILLAR Β· TRACEABLE FACT-BASE
🎯

Traceable Open Citations

Every synthesized claim connects directly to open public biomedical records from PubMed, ClinicalTrials.gov, and openFDA that you can inspect and verify.

πŸͺ™

Token-Linked Access Architecture

All platform features β€” deep literature searches, diligence passes, deck analyses, and AI research briefings β€” are linked to flexible token balances tailored for individual researchers and enterprise teams.

Common Questions

Frequently asked questions

Our moat is not prediction. Speculative AI predictions of clinical trial success are notoriously fragile and untestable. Our defensible moat is built on four core capabilities: (1) a proprietary therapeutic graph linking biological targets, disease pathways, and molecular entities; (2) structured trial intelligence capturing granular attrition, recruitment velocity, and endpoints; (3) an automated mechanistic contradiction engine highlighting conflicting literature and registry assertions; and (4) purpose-built scientific workflow UX for candidate comparison, deck auditing, and audit-ready diligence dossiers.

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Need custom target evaluation or corporate licensing?

Our team collaborates with pharma business development, venture capital funds, and academic translational centers worldwide.

Contact Our Research Team β†’
Direct Inquiries
Connect with Consult Sciences Ltd
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